While these diseases have distinct etiologies and pathologies, they all involve neuronal loss and sustained activation of the brains immune system, including microglia and astrocytes ( A key driver of neuronal injury is oxidative stress, which arises when the generation of reactive oxygen species (ROS) overwhelms the brains antioxidant defenses, one such defense being glutathione (GSH) ( GSH is the most abundant endogenous antioxidant in the brain and plays an important role in counteracting oxidative stress ( This review focuses specifically on how GSH affects immune cells in the brain, specifically CNS-resident glial cells such as microglia and astrocytes
Collectively, these results highlight FGJ as a promising functional food candidate for managing hyperglycemia and associated metabolic disorders, warranting further mechanistic studies and productdevelopment efforts
David: I have a thought
Pharmacotherapy serves as a critical adjunct to psychosocial interventions, targeting the neurobiological underpinnings of AUD [12]
There are some limitations to this systematic review
If thats you, youre far from alone
