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It is also important to be cautious of medication interactions

335,336 Further, the GLP-1/GIP dual-agonist tested in this study, MAR709, lost its superior efficacy on body weight and food intake over GLP-1 in the CNS-GIPR knockout mice, suggesting that this dual-agonist mediates part of its action via the CNS-GIPR

This cardiovascular protection could have cascading benefits throughout the body, including the brain