Can J Cardiol 2018;34:1350-61
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Any cloudiness may indicate protein aggregation, microbial contamination, or precipitation
OBrien TE, Ray JG, Chan WS
Glossary of Terms References Jastreboff AM, Kaplan LM, et al
However, several products do allow limited room temperature storage before first use according to their FDA labels: Wegovy (semaglutide): Up to 28 days at or below 86F (30C) before use Trulicity (dulaglutide): Up to 14 days at or below 86F (30C) before use Mounjaro and Zepbound (tirzepatide): Up to 21 days at or below 86F (30C) before use Bydureon BCise (exenatide extended-release): Up to 4 weeks at or below 77F (25C) before use When storing unopened GLP-1 medications, patients should keep them in their original carton to protect them from light exposure, which can also degrade the active ingredient