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GLP-1 RA weight-loss drugs could raise risk of aspiration during surgery Glucagon-like peptide-1 receptor agonist (GLP-1 RA) drug use appears to be associated with increased residual gastric content (RGC) detected by gastric ultrasonography, a major risk factor for aspiration under anesthesia

Limitations of waiting 6 months before escalation The conventional approach of waiting 6 months before adjusting treatment strategies presents substantial drawbacks for GLP-1 non-responders

Accordingly, approved indications expanded in early 2024 to include not only reduction of hyperglycemia, but also weight management in non-diabetic patients, and even cardiovascular risk reduction in patients with elevated weight and comorbid cardiovascular disease

In animal studies, oral administration of garlic preparations and organosulfur compounds was found to increase the expression and activity of phase II enzymes in a variety of tissues (64-66)

All you have to do is relax and go about your day or sleep if at night

GI side effects can worsen with alcohol consumption