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Another new insight came from knock-out of the mysterious type 2 IGF receptor, identical to the mannose-6 phosphate receptor (M6P-R), specifically binding IGF-II and involved in internalization of proteins for lysosomal degradation

Function of glutathione and glutathione disulfide in immunology and immunopathology

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In a three-month trial with older adults (ages 6077), treadmill exercise did not significantly change group-average IGF-1 levels, yet individual increases were associated with greater hippocampal volume and better verbal recall

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