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The failure of the antioxidant system to negate the pathological rise in the oxidative species is exacerbated by reduction in levels of the major cellular nucleophile, GSH due to their covalent modification by dopamine quinone species 20,43,44,45
We opted for an 80% increase in stimulation based on the consensus reached in several experimental studies conducted on rats and mice [7,17,23]
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In case of both 10 and 20 mg Se 4+ /L culture medium, a similar increase in the OD (1.18 and 1.16) was observed after 24 h incubation
Glutathione skin whitening injections have gained significant attention in recent years, promising a brighter, more even complexion