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JAMA 282 , 15681575 (1999)

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Mandal AH, Ghosh S, Adhurjya D, Chatterjee P, Samajdar I, Mukherjee D, et al

Common mild side effects include injection-site irritation or temporary water retention, but serious reactions warrant immediate protocol adjustment or discontinuation

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The primary endpoint was log-transformed and analysed using a normal linear model and an ANCOVA with hepatic status as factor and log body weight at baseline as covariate