Turned out that 90+% of the participants reported a physical benefit when taking 500 mcg in a Delayed Release capsule
Nevertheless, studies utilizing more specific biomarkers of vitamin B 12 status, including measures of holo-transcobalamin and methylmalonic acid, have shown more consistent results and a trend towards associations between poor vitamin B 12 status and faster cognitive decline and increased risk of Alzheimers disease (82-86)
Molecular and Cellular Endocrinology
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Can I use regular sterile water instead of bacteriostatic water
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