This triggers pulsatile secretion of growth hormone (GH) without significantly affecting other hormones like cortisol or prolactin
What they found: No serious adverse events triggered by AOD-9604 The most frequent side effects: headache (~5 %), occasional fatigue, at the same frequency as placebo No changes in IGF-1 levels, glycemia, blood pressure, heart rate No signals of cardiovascular, hepatic or renal toxicity Safety profile comparable to placebo Why it matters: From a safety perspective, AOD-9604 is one of the safest peptides in the clinical registry
Pain modulation Research reveals DSIP has analgesic properties
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D., & Jain, R
Li J, Amoh BK, Mccormick E et al (2023) Integration of transcriptome-wide association study with neuronal dysfunction assays provides functional genomics evidence for Parkinsons disease genes