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Factors such as duration of supplementation, dosage, and individual variability may contribute to the inconsistent L-carnitine weight loss results observed across different studies

Using both SGLT-2 and DPP-4 inhibitors as active comparators strengthened study validity, while register linkage minimized selection and recall bias by ensuring exposures were recorded independently of outcomes

GLP-1 and dual agonist therapies influence gastric emptying, insulin release, and glucose regulation

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Linnebjerg H, Kothare P, Park S, Mace K, Mitchell M

There are no large placebo-controlled human trials on the pure peptide yet, so a lot of what gets marketed as proven is inferred