Increased arginase activity is thought to play a role in childhood asthma pathogenesis, with a consequent increase in proline production leading to collagen deposition 52
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e , The distances between catalytic residues Sec46 and Trp136 were recorded every 4.8 ps throughout MD simulations of GPX4 WT (PDB: 6HN3), GPX4 K48A , GPX4 K48L , GPX4 K48E , GPX4 K48Q , and GPX4 K48R
12-OR: Urine lactate is a disease biomarker for diabetic kidney disease
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ROS signal transduction in inflammation Classically, ROS are considered lethal defense molecules that are released by neutrophils to destroy exogenous pathogens that invade the body