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With declining estrogen, you become more prone to losing lean mass and storing fat, especially around the midsection

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Another study looking at those with neurodegenerative disorders found that an infusion of NAC led to an increase of the blood GSH/GSSG ratio and levels of glutathione in the brain

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When taking these supplements in combination, research suggests an optimal pairing of 2 grams L-citrulline with 2 grams L-arginine for maximising nitric oxide production