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38-40 A multicenter study of 709 patients with COPD in China (PEACE study) treated with placebo or 1500 mg carbocisteine per day for 1 year demonstrated a reduction in the number of acute respiratory exacerbations in the active drug group

[26] did not show superiority over saline injection in their studies of infiltrative treatment with one and, for Scott's study, even two doses of PRP

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