GLP-1, short for Glucagon-like peptide-1, is a hormone that enhances insulin secretion and suppresses glucagon release, slowing down digestion
GLP-1 receptor agonist meds help regulate blood glucose by stimulating insulin secretion when blood sugar levels are high and reducing glucagon release to prevent spikes
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These drugs include: Semaglutide (Wegovy, Ozempic) Tirzepatide (Mounjaro) Liraglutide (Saxenda) Common GLP1 side effects: Nausea Vomiting Diarrhoea or constipation Bloating Stomach pain Headaches Fatigue In the STEP 1 trial, participants using semaglutide 2.4 mg (Wegovy) reported the following during the first weeks: Nausea (44.2%) Diarrhoea (29.5%) Vomiting (24.2%) Constipation (23.4%) Most symptoms subsided after the dose-titration phase
Individuals with inflammatory conditions such as psoriasis who also have metabolic comorbidities might experience dual benefits, though dedicated trials in these populations are lacking