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Finally, lysosomal and liposomal colocalization was imaged with a high-content screening system in confocal mode, and Pearson correlation coefficients were calculated by using GraphPad Prism 8.3.0 software 67

Interestingly, cysteine deprivation and activation of necroptosis are associated with the augmented activity of glutaminolysis [231], which fuels the mitochondrial Krebs cycle through the conversion of glutamate to -ketoglutarate [232]

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