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Who May Benefit and What to Discuss with Your GP Adults with obesity (BMI 30 kg/m) or overweight with weight-related comorbidities are the target population

Phase I and II clinical trials conducted have shown improved cognitive and motor function with different drugs from GLP-1RA group although the small sized and limited duration of trials have not provided a conclusive result to influence the practice, although with further advancement in ongoing trials effects observed may be noteworthy for intervention in future practice (119)

These results provide a structural framework for understanding class B GPCR activation through hormone binding

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Tirzepatide itself does not build muscle, but by lowering fat mass and improving testosterone levels indirectly, it may create better conditions for muscle growth when combined with resistance training and adequate protein intake

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