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In heterodimeric GST complexes such as those formed by the cytosolic mu and alpha classes, however, the cleft between the two subunits is home to an additional high-affinity nonsubstrate xenobiotic binding site, which may account for the enzymes' ability to form heterodimers

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10.1111/add.12850 31 KangH.XiaoX.HuangC.YuanY.TangD.DaiX.et al (2017)

VEGF Receptor Signaling and Endothelial Function

As future direction, we present evidence showing that treatment using several antioxidants through respiratory delivery, both intranasal and intrapulmonary, may offer improved success over oral and dietary delivery