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It is known for certain that IBDs are an expression of an overanxious immune response, with a recent study 104 indicating increases in inflammatory (IL-6), type-1 immunity (IL-12 p40), and immunomodulatory (transforming growth factor [TGF]-beta, IL-10) cytokines

[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Zubair S., Hafeez S., Mujtaba G

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Aging Cell 7 , 285290 (2008)

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