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When the Ipamorelin-preexposed pituitary cells were later cultured and challenged in vitro with the endogenous hormone GHRH, the Ipamorelin-primed group appeared to exert a clear increase in both the proportion of GH-immunostained somatotrophs and their intracellular growth hormone content

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A study by Liou (65) revealed that CD133 can modulate cell cycle progression by affecting Wnt signaling and promoting the invasiveness of tumor cells (64-67)

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