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doi: 10.3389/fnut.2026.1770381 Received 18 December 2025 Revised 06 January 2026 Accepted 13 January 2026 Published 22 January 2026 Volume 13 - 2026 Edited by Jing Gao, National Engineering Research Center for Oil Tea, China Reviewed by Jiayi Su, Chinese Academy of Sciences (CAS), China Chengjun Hu, Chinese Academy of Tropical Agricultural Sciences, China Updates Copyright 2026 Ma, Azad, Yu, Sun, Zhang, Pi and Wu

These conformational changes are stabilized by additional noncovalent interactions involving the conserved residues, such as the Arg121 making hydrogen bonds with Asp67 to further strengthen the pi-cation interactions involving Trp72, Arg102, and Trp110 (see Figure 4 inset 2)

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