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2041 Dynamic Screening Nutritional Risk Index on Treatment Tolerance and Hospitalization Costs in Cancer Patient: A 3-Year Longitudinal Cohort Study Hongfan Yu 1 , Li Tang 2 , Qiuling Shi 1 , Xing Wei 3 1 State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, China, 2 Shaoxing Second Hospital, Shaoxing, China, 3 Department of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital of the University of Electronic Science and Technology of China, Chengdu, China Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :2041 Aims Assessment of the advanced cancer patient developing malnutrition has been limited to cross-sectional design

However, despite its potential, CAR-T-cell therapy targeting CSCs presents several challenges, including tumor heterogeneity, antigen escape, and an immunosuppressive TME, all of which limit its therapeutic efficacy

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