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These events affected approximately 4% of the participants in both the retatrutide and placebo groups, indicating that the incidence was similar between the treatment and control arms

Daratumumab: a first-in-class CD38 monoclonal antibody for the treatment of multiple myeloma

& Noelle, R

Furthermore, unscheduled glycolysis and glycolytic overload in enteroendocrine cells and neurons are speculated to exacerbate impairment of the incretin effect, creating a systemic landscape of resistance that links organelle failure to clinical metabolic decline (Meier and Nauck, 2010

Funding This work was supported by the Health Special Project fund of PLA (21BJZ43)