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Separate sources discuss BPC-157 in tendon explants and fibroblasts, thymosin beta-4 in rat and keratinocyte models, GHK-Cu laboratory research, and KPV cell and mouse systems

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According to the SmPC, Wegovy commonly causes nausea, vomiting, diarrhoea, constipation, and abdominal discomfort, particularly during dose escalation

Studies of both rats and humans have shown that induction of the KD leads to a reduction in both abundance and diversity of gut microbes (10, 65)

It ties that pattern to GLP-1 receptor activation delaying gastric emptying and decreasing peristalsis, the contractions that move stool through the colon