Here is what participants achieved on average: Mounjaro (tirzepatide 15mg) SURMOUNT-1: Week 4: approximately 2 to 3% body weight loss Week 12: approximately 7 to 8% Week 24: approximately 13 to 15% Week 52: approximately 18 to 20% Week 72 (end of trial): average 20.9% Wegovy (semaglutide 2.4mg) STEP 1: Week 4: approximately 1 to 2% body weight loss Week 12: approximately 5 to 6% Week 24: approximately 9 to 10% Week 52: approximately 12 to 14% Week 68 (end of trial): average 14.9% These are averages
You might notice that meals that previously satisfied you now feel too large, or that cravings for specific foods diminish noticeably by day three or four
10.1038/ki.2008.109 Kidney Int
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Venoji R, Amirtharaj GJ, Kini A, Vanaparthi S, Venkatraman A, Ramachandran A
7 Department of Biochemistry, 8 Department of Medicine, and 9 Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada