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Before starting Janumet, doctors assess kidney function, which may be contraindicated in severe cases

The study followed patients for up to two years to assess discontinuation (e.g., stopping their GLP-1 RA) and for an additional two years to monitor reinitiation (e.g., restarting a GLP-1 RA)

Pediatr Nephrol 39:11131123

Both medications influence serotonin pathways, though through different mechanismssemaglutide affects appetite-control neurons while Lexapro modulates mood-regulating circuits throughout the brain

The undigested material becomes bacterial substrate, producing gas

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