Information was retrieved from RefSeq ( [30] and Uniprot ( [31] databases (TIFF 128 kb) Supplementary Figure 3 (download TIF Confirmed transcript variants of GSTO1, GSTO2, GSTP1 and GSTS1
In the cMap genes are represented by probe set IDs in the tag lists, which identify the up- and downregulated genes
Glossary 2-AG 2-arachidonoylglycerol 5-HT1A 5-hydroxytryptamine receptor 1A (serotonin receptor 1A) AEA anandamide BBB bloodbrain barrier BDNF brain-derived neurotrophic factor BrdU bromodeoxyuridine CB1R cannabinoid receptor 1 CB2R cannabinoid receptor 2 CBD cannabidiol CBP cannabis-based products CNS central nervous system COX-2 cyclooxygenase-2 DCX doublecortin ECS endocannabinoid system FAAH fatty acid amide hydrolase GFAP glial fibrillary acidic protein GSH/GSSG reduced glutathione/oxidized glutathione ratio GSK-3 glycogen synthase kinase 3 beta IFG inflammaging IGF-2 insulin-like growth factor 2 IL-1 interleukin-1 IL-6 interleukin-6 LPS lipopolysaccharide MDMA 3,4-methylenedioxymethamphetamine MWT Morris water maze (test) NF-B nuclear factor kappa-light-chain-enhancer of activated B cells NO nitric oxide NOR novel object recognition (test) Ph
NAD + is reduced by 70% within 3 to 24 months, and as a compensation, the concentration of NADH has increased by 50%
These products avoid any harsh chemical methods that strip the raw ingredients of their nutritional value to give you substandard products
A carefully thought-out diet can greatly increase the benefits of GLP-1 drugs, even though they are effective on their own
