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Nanmoins, il est important de connatre les effets secondaires potentiels et les contre-indications lis son utilisation

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For each study, the risk of bias was measured with the Cochrane Risk of Bias tool (ROB 2.0) [20]

While there is extensive evidence of improvement in metabolic parameters with even modest weight reductions of 310%, some complications of obesity such as OSA or OA, may require more substantial weight reduction to realize clinically meaningful improvements or resolution

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