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The body uses several coordinated mechanisms to make this happen: Relaxation of the gastric fundus leads to increased gastric compliance Inhibition of antral contractility reduces propulsive forces Increased pyloric tone creates greater resistance to outflow [2] Research points to the vagal nerve pathway as the main route for this action

J Stud Alcohol Drugs 85:510 Brunchmann A, Thomsen M, Fink-Jensen A (2019) The effect of glucagon-like peptide-1 (GLP-1) receptor agonists on substance use disorder (SUD)-related behavioural effects of drugs and alcohol: a systematic review

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The numbers from research settings represent averages and do not guarantee what any one person will experience