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Key takeaway for GLP-1 therapy and muscle: the body rebalances tissues as weight and energy needs decline

FIGURE 7 Previous studies have shown that deferoxamine (DFO) inhibits the growth of esophageal squamous cell carcinoma (ESCC) cells by activating the ERK pathway in a ROS-dependent manner (Supplementary Figure S3E), and treatment with 800 M CGA led to a significant increase in ROS accumulation in hepatocytes (Figures 7F,G)