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[15] [19] The homeostatic model assessment of insulin resistance (HOMA-IR), a validated surrogate marker calculated from fasting glucose and insulin levels, has shown improvement in patients treated with semaglutide

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Testing variants in GLP1R, GIPR, FTO, and MC4R helps personalize whether injectable or oral therapy, and which compound (semaglutide, tirzepatide, or dual GLP-Squared) may work best for your unique biology

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