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In this study, tirzepatide was compared to a placebo (SURMOUNT-1)

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Therefore, targeted activation of antioxidant systems, especially the GSH system, is an essential treatment strategy to protect cardiomyocytes against oxidative damage

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NMO is mainly caused by auto-anti-AQP4 antibodies 282 that initially attack astrocytic endfeet, 283 leading to complement-mediated lysis and destruction of the glial limitans and astrocyte degeneration, which in turn cause the other pathophysiological sequalae (Fig

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