C., Ibi, A., Wood, S., Hardy, M., Gahler, R
But, theres a catch If you have ileitis (inflammation of the ileium), Crohns Disease affecting your stomach or small intestine, or have had a bowel resection, chances are that you might be deficient in B12 because you arent able to properly absorb it through your gut (SOURCE)
This downregulation leads to the accumulation of the intermediate 3-hydroxy-lanost-8-en-32-al, a known translational repressor of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR)
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It may also be considered as part of broader longevity planning
Routes of Administration Subcutaneous injection (standard): Protocols describe injection in the abdomen, thigh, or upper arm, rotating sites between injections, using standard SC technique with a 29-31 gauge insulin syringe