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While purine nucleotide synthesis is selectively affected through Nrf2 activation, c-Myc is involved in the regulation of both purine and pyrimidine nucleotide synthesis

[7] It turns out that NAC supplementation enhances muscle cysteine and glutathione levels and prevents fatigue during endurance training in athletes, [8] which may seem like a more bioavailable solution in the first place

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In this section we expand on these concepts

Further details describing tissue collection, tumor classification and metabolomic profiling analyses have been presented elsewhere [40]