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Spermatozoa are vulnerable to ROS because their plasma membrane and cytoplasm contain large amounts of polyunsaturated fatty acids (Alvarez & Storey, 1995), resulting in a decrease in sperm motility, presumably by a rapid loss of intracellular ATP, causing axonemal damage (de Lamirande & Gagnon, 1992), a decrease in sperm viability and an increase in mid-piece morphology defects, with deleterious effects on sperm capacitation and acrosome reaction

Cinnamaldehyde suppresses NLRP3 derived IL-1 via activating succinate/HIF-1 in rheumatoid arthritis rats

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The only contraindication is a personal or family history of medullary thyroid carcinoma

Dosis diaria recomendada: 500 mg (aprox 3 cacitos)

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