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Recreational activities including tennis, golf, and gardening also contribute

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Inconsistent dosing, including skipped doses, schedule changes without medical guidance, or stopping treatment too early

GraphPad Prism 7 software was used for the statistical calculations (GraphPad Inc., La Jolla, CA, USA)

It also reduces B12 absorption in the small intestine by interfering with a calcium-dependent mechanism that helps the B12-intrinsic factor complex attach to the gut wall