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Recent work suggests an interaction with the JAK-2/STAT-3 pathway, involved in the inflammatory response and cell survival, reinforcing the hypothesis of a pleiotropic mechanism of action

Jiang W, Wu N, Wang X, Chi Y, Zhang Y, Qiu X, Hu Y, Li J, Liu Y (2015) Dysbiosis gut microbiota associated with inflammation and impaired mucosal immune function in intestine of humans with non-alcoholic fatty liver disease

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The multiple roles of Bub1 in chromosome segregation during mitosis and meiosis