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doi:10.1111/dom.16275 Funding/Conflicts: Public Funding: From the study, no public funding source was reported

Retatrutide has a half-life of approximately 6 days, supporting weekly dosing in research models

Biomarker and Genetic Factors Influencing Concurrent Use Individual variation in oxidative stress response and antioxidant capacity is partly determined by genetic polymorphisms in pathways that regulate GLP-1 signaling, energy metabolism, and inflammation

Other antioxidants including Korean red ginseng (Song et al., 2011), Petroselinum Crispum (Khosravan et al., 2017), and orchid extracts were also considered in melasma treatment and showed favorable efficacy and tolerability (Tadokoro et al., 2010)