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43 In a mouse model of T-cell-induced acute diarrhea, epithelial barrier dysfunction was associated with an abrupt increase in phospho (P)-MLC expression

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While eating close to bedtime is generally not advised, a carefully chosen bedtime snack may be helpful for avoiding nighttime hunger in some circumstances, especially in individuals prone to low blood glucose levels during the night

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Side effects may be more noticeable when starting treatment or after dose increases