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For autoimmune patients whose conditions have a gut component, which includes most of them to varying degrees, the local gut effects of GLP-1 receptor activation may contribute to systemic immune improvement
Dose reduction as weight targets are reached Phase 3 trial protocols allow dose reduction when a participant's BMI drops to 22 kg/m or below, or when there is perceived excessive weight loss
Lara AH, Kennerley SW, Wallis JD
What Clinical Studies Say About Dosage One of the biggest studies on retatrutide found that people lost up to 24.2% of their body weight after 48 weeks
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