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(2012) characterized GHK-Cus effects on over 4,000 human genes using microarray analysis, demonstrating broad modulation of tissue remodeling, antioxidant, and growth factor pathways [1]

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In a phase 2 clinical trial for obesity, 26 weeks of efinopegdutide (doses 5 to 10mg) resulted in up to 11.8% WL in people with obesity (without diabetes) compared to 7.5% WL with liraglutide 3 mg and 1.8% WL with placebo [77, 78]