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The compounding process takes 57 business days, ensuring each dose is prepared fresh for the patient

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But even there, we think the impact is more micro than macro

It does mean that buyers who start a compounded GLP-1 program in mid-2026 should be aware of how quickly the regulatory picture may shift, and should discuss continuity of care planning with their assigned clinical provider before committing to a multi-month program

The GI side effects can be linked to the accumulation of metformin in gut enterocytes and enhanced glucose utilization resulting in lactate generation, as well as metformin-induced changes in the microbiota (6, 10)

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