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Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells

(2020) 8(8):CD007807

On day 15, 30 minutes after administration of the treatments, animals performed the Morris water maze test

Moderate ROS can reinforce PI3K/AKT/mTORC1 activation, whereas excessive accumulation induces oxidative stress and inactivates key components, shifting the balance toward cell death [48, 49]

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