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A Phase 2 substudy found that retatrutide produced up to 26.1% reduction in total body fat mass while limiting lean mass loss to 6.5kg

Regarding the primary end point, the mean change in BMI from baseline, participants in the study receiving setmelanotide therapy (n=94) experienced a 15.8% reduction

Researchers should always review product labeling and follow applicable storage guidelines to help maintain product quality and integrity throughout its intended shelf life

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The study was done from May 2009 to December 2011

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