Ive had patients spend thousands of dollars on compounded versions and barely lose any weight
Jacobsen, L
doi: 10.1152/ajprenal.00527.2014 28 JiaY.ZhengZ.GuanM.ZhangQ.LiY.WangL.et al
For example, previous research has shown that females appear to be more sensitive to the ability of GLP-1R agonists to suppress food intake and body weight (e.g., Richard et al., 2016)
Potential Negative Effects on Mental Health While the potential benefits are encouraging, its crucial to acknowledge the potential negative impacts of GLP-1 inhibitors on mental health: Increased Anxiety and Agitation: Paradoxically, while some studies suggest anxiety reduction, others have reported instances of increased anxiety, restlessness, and agitation in individuals taking GLP-1 agonists
Myostatin is a member of the transforming growth factor beta (TGF) superfamily of growth factors that regulates catabolism of skeletal muscle 9,10,11 , making it an attractive target for muscle atrophy and for preserving muscle during pharmacologic weight loss 12,13