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3.3 Insulin response In the prediabetes group, treatment with linagliptin did not alter fasting and postload serum insulin levels in prediabetes in both the low and high GLP-1 groups ( Table 3 , Figures 3AC )

Although S mimicry of the host coatomer-binding dibasic motif ensures retrograde trafficking to the ERGIC, avoidance of the host-like C-terminal acidic residue is critical for S-coatomer dissociation and therefore incorporation into virions or export for cell-cell fusion

These compounds may influence neurotransmitters, stress response pathways, and cognitive processes such as focus, memory, and mood regulation

Adjusting the dose titration schedule if needed (e.g., staying at a lower dose longer if side effects are problematic)

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HardingBNAguilarREspinosaACastao-VinyalsGPapantoniouKNavarreteJMet al