Uses * Control blood sugar in type 2 diabetes * Reduce risk of cardiovascular events in some diabetic patients * Promotes weight loss * Sometimes used off-label for obesity management Mechanism of action Ozempic works by: * Increasing insulin release when blood glucose is high * Reducing glucagon secretion * Slowing gastric emptying * Reducing appetite Administration * Given as a subcutaneous injection * Usually injected once weekly * Common injection sites: * Abdomen * Thigh * Upper arm Common side effects * Nausea * Vomiting * Diarrhea * Constipation * Abdominal pain * Loss of appetite Serious adverse effects * Pancreatitis * Gallbladder disease * Severe dehydration * Kidney injury * Hypoglycemia (especially with insulin or sulfonylureas) * Possible thyroid C-cell tumor risk Contraindications * Personal or family history of medullary thyroid carcinoma * Multiple endocrine neoplasia type 2 (MEN2) * Severe hypersensitivity to semaglutide Monitoring * Blood glucose and HbA1c * Weight * Renal function * Signs of pancreatitis Important points * Not used for type 1 diabetes * Should be combined with diet and exercise * Dose is increased gradually to reduce gastrointestinal side effects * Stopping suddenly may lead to weight regain or worsening glucose control Drug interactions Caution with: * Insulin * Sulfonylureas * Oral medications affected by delayed gastric emptying To view or add a comment, sign in More Relevant Posts Exercise caution before popping a pill
Q: What are the limitations and drawbacks of relying solely on GLP-1 medications for weight management
Below, each of the shared root causes gets its own section, followed by a quick reference table so you can match your symptom to the most likely cause and what to check first
Communicate openly with your PlexusDx provider about your experienceyour dose may need adjustment, but your price won't change
Grilo CM, Crosby RD, Peterson CB, Masheb RM, White MA, Crow SJ, et al
Do not wait for symptoms to worsen
