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Metabolism The metabolism of common GLP-1 RAs varies across agents: Exenatide undergoes hydrolysis in the kidneys and liver, producing smaller inactive peptides excreted via the kidneys (23)

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In summary, our study demonstrates that S-allyl-L-cysteine (SAC) alleviates UC by suppressing ferroptosis and oxidative damage in colonic epithelial cells through the Keap1/Nrf2/GPX4 signaling axis-mediated regulation of glutathione (GSH) metabolism

To date, only injectable formulations have been approved by regulatory agencies

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10.3389/fimmu.2015.00386 158 RosenstockJ.Aguilar-SalinasC.KleinE.NepalS.ListJ.ChenR.et al (2009b)