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He found that children born with a genetic disorder called homocystinuria, which causes the homocysteine levels to be very high, often died at a very young age with advanced atherosclerosis in their arteries

Such unwanted side effects include undesired tachycardia, increased lactic acidosis, cardiac arrhythmias (including atrial fibrillation) as well as the development of refractory shock (DeBacker et al, 2010

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