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This regulatory mechanism may stem from its detergent-like effect, which affects the structure and function of the cell membrane [122]

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People with a lower starting body mass index tended to lose the highest percentage, while those carrying more weight lost a larger absolute number of pounds even if the percentage read lower

Through the integrin-FAK-YAP/TAZ signaling pathway, they mediate the nuclear translocation of YAP/TAZ, which, upon binding to the TEAD transcription factor, upregulates fibrosis-related target genes such as Col1A1, -SMA, and TGF-1, thereby inducing the transformation of fibroblasts into myofibroblasts (133)

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doi: 10.1021/acs.jafc.1c01813 33 Efsa Panel on Nutrition, Novel Foods and Food Allergens (NDA)TurckD.BohnT.CastenmillerJ.De HenauwS.Hirsch-ErnstK