Specifically, to avoid lipid peroxidation reactions dependent on experimental settings, authors proposed to exclude oxygen or add high amounts of butylhydroxytoluene (BHT) (Jentzsch et al., 1996)
Abrupt withdrawal has been linked to severe complications, including Posterior Reversible Encephalopathy Syndrome (PRES), hypertensive encephalopathy, stroke, and death (Thorpe et al., 2025)
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System Xc is an antiporter composed of SLC7A11 and SLC3A2, which mediates the cellular uptake of extracellular cystine for GSH synthesis ( 3 Ferroptosis in PCOS 3.1 Core pathophysiological features of PCOS and ferroptosis Ovulatory dysfunction in PCOS often leads to oligomenorrhea or amenorrhea, which reduces iron loss through menstruation
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